Publication: Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth.
Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth.
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Wittwer, F., van der Straten, A., Keleman, K., Dickson, B. J., & Hafen, E. (2001). Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth. Development, 128(5), 791–800.
Abstract
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Abstract
Members of the AF4/FMR2 family of nuclear proteins are involved in human diseases such as acute lymphoblastic leukemia and mental retardation. Here we report the identification and characterization of the Drosophila lilliputian (lilli) gene, which encodes a nuclear protein related to mammalian AF4 and FMR2. Mutations in lilli suppress excessive neuronal differentiation in response to a constitutively active form of Raf in the eye. In the wild type, Lilli has a partially redundant function in the Ras/MAPK pathway in differentiation but
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- Wittwer, F
- van der Straten, A
- Keleman, K
- Dickson, B J
- Hafen, E
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Wittwer, F., van der Straten, A., Keleman, K., Dickson, B. J., & Hafen, E. (2001). Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth. Development, 128(5), 791–800.
