Publication: Multiplexed Imaging-based Profiling of Immunological Synapses as a Novel Tool for Characterization of Cytotoxicity Defects in Primary Immunodeficiencies
Multiplexed Imaging-based Profiling of Immunological Synapses as a Novel Tool for Characterization of Cytotoxicity Defects in Primary Immunodeficiencies
Date
Date
Date
Citations
Koovely, D. (2024). Multiplexed Imaging-based Profiling of Immunological Synapses as a Novel Tool for Characterization of Cytotoxicity Defects in Primary Immunodeficiencies. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258792
Abstract
Abstract
Abstract
Cytotoxic lymphocytes are a subset of immune cells with key roles in host defense against viral infections, against tumors as well as in self-regulation of immunity. Cytotoxic lymphocytes kill target cells by triggering cell death pathways with direct cell-cell contacts. To ensure the specificity and efficiency of killing, cytotoxic lymphocytes form a specialized structure named cytotoxic immunological synapse (IS) with their target cell. The IS is composed of adhesion molecules, signaling molecules, and cytoskeletal components that c
Metrics
Downloads
Views
Citations
Additional indexing
Creators (Authors)
Faculty
Faculty
Faculty
Item Type
Item Type
Item Type
Referees
Language
Language
Language
Place of Publication
Place of Publication
Place of Publication
Publication date
Publication date
Publication date
Date available
Date available
Date available
Number of pages
Number of pages
Number of pages
OA Status
OA Status
OA Status
Metrics
Downloads
Views
Citations
Citations
Koovely, D. (2024). Multiplexed Imaging-based Profiling of Immunological Synapses as a Novel Tool for Characterization of Cytotoxicity Defects in Primary Immunodeficiencies. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-258792
