Publication: BK Polyomavirus Serotype-Specific Antibody Responses in Blood Donors and Kidney Transplant Recipients with and without New-Onset BK Polyomavirus-DNAemia : A Swiss Transplant Cohort Study
BK Polyomavirus Serotype-Specific Antibody Responses in Blood Donors and Kidney Transplant Recipients with and without New-Onset BK Polyomavirus-DNAemia : A Swiss Transplant Cohort Study
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Hillenbrand, C. A., Akbari Bani, D., Follonier, O., Kaur, A., Weissbach, F. H., Wernli, M., Wilhelm, M., Leuzinger, K., Binet, I., Bochud, P.-Y., Golshayan, D., Hirzel, C., Manuel, O., Mueller, N. J., Schaub, S., Schachtner, T., van Delden, C., Hirsch, H. H., & Swiss Transplant Cohort Study. (2025). BK Polyomavirus Serotype-Specific Antibody Responses in Blood Donors and Kidney Transplant Recipients with and without New-Onset BK Polyomavirus-DNAemia : A Swiss Transplant Cohort Study. American Journal of Transplantation, 25, 985–1001. https://doi.org/10.1016/j.ajt.2024.11.019
Abstract
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Abstract
BK polyomavirus (BKPyV) causes premature renal failure in 10% to 30% of kidney transplant recipients (KTRs). Current guidelines recommend screening for new-onset BKPyV-DNAemia/nephropathy and reducing immunosuppression to regain BKPyV-specific immune control. Because BKPyV encompasses 4 major genotype (gt)-encoded serotypes (st1,-2,-3,-4), st-specific antibodies may inform the risk and course of BKPyV-DNAemia/nephropathy. Using BKPyV st-virus-like particle (VLP) enzyme-linked immunosorbent assay, we analyzed plasma from 399 blood dono
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- Hillenbrand, Caroline A
- Akbari Bani, Dorssa
- Follonier, Océane
- Kaur, Amandeep
- Weissbach, Fabian H
- Wernli, Marion
- Wilhelm, Maud
- Leuzinger, Karoline
- Binet, Isabelle
- Bochud, Pierre-Yves
- Golshayan, Dela
- Hirzel, Cédric
- Manuel, Oriol
- Mueller, Nicolas J
- Schaub, Stefan
- van Delden, Christian
- Hirsch, Hans H
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Hillenbrand, C. A., Akbari Bani, D., Follonier, O., Kaur, A., Weissbach, F. H., Wernli, M., Wilhelm, M., Leuzinger, K., Binet, I., Bochud, P.-Y., Golshayan, D., Hirzel, C., Manuel, O., Mueller, N. J., Schaub, S., Schachtner, T., van Delden, C., Hirsch, H. H., & Swiss Transplant Cohort Study. (2025). BK Polyomavirus Serotype-Specific Antibody Responses in Blood Donors and Kidney Transplant Recipients with and without New-Onset BK Polyomavirus-DNAemia : A Swiss Transplant Cohort Study. American Journal of Transplantation, 25, 985–1001. https://doi.org/10.1016/j.ajt.2024.11.019
