Publication: Mechanisms of Gurken-dependent pipe regulation and the robustness of dorsoventral patterning in Drosophila
Mechanisms of Gurken-dependent pipe regulation and the robustness of dorsoventral patterning in Drosophila
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Peri, F., Technau, M., & Roth, S. (2002). Mechanisms of Gurken-dependent pipe regulation and the robustness of dorsoventral patterning in Drosophila. Development, 129(12), 2965–2975. https://dev.biologists.org/content/develop/129/12/2965.full.pdf
Abstract
Abstract
Abstract
The restriction of Pipe, a potential glycosaminoglycan-modifying enzyme, to ventral follicle cells of the egg chamber is essential for dorsoventral axis formation in the Drosophila embryo. pipe repression depends on the TGFalpha-like ligand Gurken, which activates the Drosophila EGF receptor in dorsal follicle cells. An analysis of Raf mutant clones shows that EGF signalling is required cell-autonomously in all dorsal follicle cells along the anteroposterior axis of the egg chamber to repress pipe. However, the autoactivation of EGF s
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- Peri, Francesca
- Technau, Martin
- Roth, Siegfried
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Peri, F., Technau, M., & Roth, S. (2002). Mechanisms of Gurken-dependent pipe regulation and the robustness of dorsoventral patterning in Drosophila. Development, 129(12), 2965–2975. https://dev.biologists.org/content/develop/129/12/2965.full.pdf
