Publication: Mammalian sphingoid bases: Biophysical, physiological and pathological properties
Mammalian sphingoid bases: Biophysical, physiological and pathological properties
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Carreira, A. C., Santos, T. C., Lone, M. A., Zupančič, E., Lloyd-Evans, E., de Almeida, R. F. M., Hornemann, T., & Silva, L. C. (2019). Mammalian sphingoid bases: Biophysical, physiological and pathological properties. Progress in Lipid Research, 75, 100988. https://doi.org/10.1016/j.plipres.2019.100988
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Sphingoid bases encompass a group of long chain amino alcohols which form the essential structure of sphingolipids. Over the last years, these amphiphilic molecules were moving more and more into the focus of biomedical research due to their role as bioactive molecules. In fact, free sphingoid bases interact with specific receptors and target molecules, and have been associated with numerous biological and physiological processes. In addition, they can modulate the biophysical properties of biological membranes. Several human diseases
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Carreira, A. C., Santos, T. C., Lone, M. A., Zupančič, E., Lloyd-Evans, E., de Almeida, R. F. M., Hornemann, T., & Silva, L. C. (2019). Mammalian sphingoid bases: Biophysical, physiological and pathological properties. Progress in Lipid Research, 75, 100988. https://doi.org/10.1016/j.plipres.2019.100988