Publication:

Immunohistochemical PSMA expression patterns of primary prostate cancer tissue are associated with the detection rate of biochemical recurrence with 68Ga-PSMA-11-PET

Date

Date

Date
2020
Journal Article
Published version

Citations

Citation copied

Ferraro, D. A., Rüschoff, J. H., Muehlematter, U. J., Kranzbühler, B., Müller, J., Messerli, M., Husmann, L., Hermanns, T., Eberli, D., Rupp, N. J., & Burger, I. A. (2020). Immunohistochemical PSMA expression patterns of primary prostate cancer tissue are associated with the detection rate of biochemical recurrence with 68Ga-PSMA-11-PET. Theranostics, 10(14), 6082–6094. https://doi.org/10.7150/thno.44584

Abstract

Abstract

Abstract

Prostate-specific membrane antigen (PSMA) targeted PET has a high detection rate for biochemical recurrence (BCR) of prostate cancer (PCa). Nevertheless, even at high prostate-specific antigen (PSA) levels (> 3 ng/ml), a relevant number of PSMA-PET scans are negative, mainly due to PSMA-negative PCa. Our objective was to investigate whether PSMA-expression patterns of the primary tumour on immunohistochemistry (IHC) are associated with PSMA-PET detection rate of recurrent PCa. Methods: Retrospective institutional review board approved

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4 since deposited on 2020-12-10
Acq. date: 2025-11-14

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3 since deposited on 2020-12-10
Acq. date: 2025-11-14

Additional indexing

Creators (Authors)

  • Ferraro, Daniela A
    affiliation.icon.alt
  • Rüschoff, Jan H
    affiliation.icon.alt
  • Muehlematter, Urs J
    affiliation.icon.alt
  • Kranzbühler, Benedikt
    affiliation.icon.alt
  • Müller, Julian
    affiliation.icon.alt
  • Messerli, Michael
    affiliation.icon.alt
  • Husmann, Lars
    affiliation.icon.alt
  • Hermanns, Thomas
    affiliation.icon.alt
  • Eberli, Daniel
    affiliation.icon.alt
  • Rupp, Niels J
    affiliation.icon.alt
  • Burger, Irene A
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
10

Number

Number

Number
14

Page range/Item number

Page range/Item number

Page range/Item number
6082

Page end

Page end

Page end
6094

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2020

Date available

Date available

Date available
2020-12-10

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1838-7640

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

4 since deposited on 2020-12-10
Acq. date: 2025-11-14

Views

3 since deposited on 2020-12-10
Acq. date: 2025-11-14

Citations

Citation copied

Ferraro, D. A., Rüschoff, J. H., Muehlematter, U. J., Kranzbühler, B., Müller, J., Messerli, M., Husmann, L., Hermanns, T., Eberli, D., Rupp, N. J., & Burger, I. A. (2020). Immunohistochemical PSMA expression patterns of primary prostate cancer tissue are associated with the detection rate of biochemical recurrence with 68Ga-PSMA-11-PET. Theranostics, 10(14), 6082–6094. https://doi.org/10.7150/thno.44584

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