Publication: Phenotypical heterogeneity in responder (R) and non-responder (NR) male ApoE*3Leiden.CETP mice
Phenotypical heterogeneity in responder (R) and non-responder (NR) male ApoE*3Leiden.CETP mice
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Tarasco, E., Pellegrini, G., Whiting, L., & Lutz, T. A. (2018). Phenotypical heterogeneity in responder (R) and non-responder (NR) male ApoE*3Leiden.CETP mice. American Journal Of Physiology. Gastrointestinal And Liver Physiology, 315, G602–G617. https://doi.org/10.1152/ajpgi.00081.2018
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The metabolic syndrome (MetS) is a major health issue worldwide and is associated with obesity, insulin resistance, and hypercholesterolemia. Several animal models were used to describe the MetS, however many of them do not mimic well the MetS pathophysiology in humans. The ApoE*3Leiden.CETP mouse model overcomes part of this limitation, since they have a humanised lipoprotein metabolism and a heterogeneous response to MetS, similarly to humans. The reported heterogeneity among them and their common classification into responder (R) a
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- Tarasco, Erika
- Pellegrini, Giovanni
- Whiting, Lynda
- Lutz, Thomas A
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Tarasco, E., Pellegrini, G., Whiting, L., & Lutz, T. A. (2018). Phenotypical heterogeneity in responder (R) and non-responder (NR) male ApoE*3Leiden.CETP mice. American Journal Of Physiology. Gastrointestinal And Liver Physiology, 315, G602–G617. https://doi.org/10.1152/ajpgi.00081.2018
