Publication: Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis
Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis
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Gruenbaum-Cohen, Y., Tucker, A. S., Haze, A., Shilo, D., Taylor, A. L., Shay, B., Sharpe, P. T., Mitsiadis, T. A., Ornoy, A., Blumenfeld, A., & Deutsch, D. (2008). Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis. Journal of Experimental Zoology. Part B: Molecular and Developmental Evolution, 312B(5), 445–457. https://doi.org/10.1002/jez.b.21255
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The amelogenins comprise 90% of the developing extracellular enamel matrix proteins and play a major role in the biomineralization and structural organization of enamel. Amelogenins were also detected, in smaller amounts, in postnatal calcifying mesenchymal tissues, and in several nonmineralizing tissues including brain. Low molecular mass amelogenin isoforms were suggested to have signaling activity; to produce ectopically chondrogenic and osteogenic-like tissue and to affect mouse tooth germ differentiation in vitro. Recently, some
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- Gruenbaum-Cohen, Y
- Tucker, A S
- Haze, A
- Shilo, D
- Taylor, A L
- Shay, B
- Sharpe, P T
- Mitsiadis, T A
- Ornoy, A
- Blumenfeld, A
- Deutsch, D
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Gruenbaum-Cohen, Y., Tucker, A. S., Haze, A., Shilo, D., Taylor, A. L., Shay, B., Sharpe, P. T., Mitsiadis, T. A., Ornoy, A., Blumenfeld, A., & Deutsch, D. (2008). Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis. Journal of Experimental Zoology. Part B: Molecular and Developmental Evolution, 312B(5), 445–457. https://doi.org/10.1002/jez.b.21255
