Publication: Clearance by Microglia Depends on Packaging of Phagosomes into a Unique Cellular Compartment
Clearance by Microglia Depends on Packaging of Phagosomes into a Unique Cellular Compartment
Date
Date
Date
Citations
Villani, A., Benjaminsen, J., Moritz, C., Henke, K., Hartmann, J., Norlin, N., Richter, K., Schieber, N. L., Franke, T., Schwab, Y., & Peri, F. (2019). Clearance by Microglia Depends on Packaging of Phagosomes into a Unique Cellular Compartment. Developmental Cell, 49(1), 77-88.e7. https://doi.org/10.1016/j.devcel.2019.02.014
Abstract
Abstract
Abstract
Phagocytic immune cells such as microglia can engulf and process pathogens and dying cells with high efficiency while still maintaining their dynamic behavior and morphology. Effective intracellular processing of ingested cells is likely to be crucial for microglial function, but the underlying cellular mechanisms are poorly understood. Using both living fish embryos and mammalian macrophages, we show that processing depends on the shrinkage and packaging of phagosomes into a unique cellular compartment, the gastrosome, with distinct
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Villani, Ambra
- Benjaminsen, Jørgen
- Moritz, Christian
- Henke, Katrin
- Hartmann, Jonas
- Norlin, Nils
- Richter, Kerstin
- Schieber, Nicole L
- Franke, Tilman
- Schwab, Yannick
- Peri, Francesca
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Downloads
Views
Citations
Villani, A., Benjaminsen, J., Moritz, C., Henke, K., Hartmann, J., Norlin, N., Richter, K., Schieber, N. L., Franke, T., Schwab, Y., & Peri, F. (2019). Clearance by Microglia Depends on Packaging of Phagosomes into a Unique Cellular Compartment. Developmental Cell, 49(1), 77-88.e7. https://doi.org/10.1016/j.devcel.2019.02.014
