Publication: Increased porosity of electrospun hybrid scaffolds improved bladder tissue regeneration
Increased porosity of electrospun hybrid scaffolds improved bladder tissue regeneration
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Maya, H., Vincent, M., Nötzli, S., Madduri, S., Tullio, S., Rita, G., & Eberli, D. (2014). Increased porosity of electrospun hybrid scaffolds improved bladder tissue regeneration. Journal of Biomedical Materials Research. Part A, 102(7), 2116–2124. https://doi.org/10.1002/jbm.a.34889
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The object of this study was to investigate the role of scaffold porosity on tissue ingrowth using hybrid scaffolds consisting of bladder acellular matrix and electrospun poly (lactide-co-glycolide) (PLGA) microfibers that mimic the morphological characteristics of the bladder wall in vitro and in vivo. We compared single-spun (SS) PLGA scaffolds with more porous cospun (CS) scaffolds (PLGA and polyethylene glycol). Scaffolds were characterized by scanning electron microscopy. Bladder smooth muscle cells (SMCs) were seeded, and prolif
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- Nötzli, Sarah
- Madduri, Srinivas
- Eberli, Daniel
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Maya, H., Vincent, M., Nötzli, S., Madduri, S., Tullio, S., Rita, G., & Eberli, D. (2014). Increased porosity of electrospun hybrid scaffolds improved bladder tissue regeneration. Journal of Biomedical Materials Research. Part A, 102(7), 2116–2124. https://doi.org/10.1002/jbm.a.34889