Publication: Effect of N-Vinyl-2-Pyrrolidone (NVP), a Bromodomain-Binding Small Chemical, on Osteoblast and Osteoclast Differentiation and Its Potential Application for Bone Regeneration
Effect of N-Vinyl-2-Pyrrolidone (NVP), a Bromodomain-Binding Small Chemical, on Osteoblast and Osteoclast Differentiation and Its Potential Application for Bone Regeneration
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Klemmer, V. A., Khera, N., Siegenthaler, B. M., Bhattacharya, I., Weber, F. E., & Ghayor, C. (2021). Effect of N-Vinyl-2-Pyrrolidone (NVP), a Bromodomain-Binding Small Chemical, on Osteoblast and Osteoclast Differentiation and Its Potential Application for Bone Regeneration. International Journal of Molecular Sciences, 22(20), 11052. https://doi.org/10.3390/ijms222011052
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The human skeleton is a dynamic and remarkably organized organ system that provides mechanical support and performs a variety of additional functions. Bone tissue undergoes constant remodeling; an essential process to adapt architecture/resistance to growth and mechanical needs, but also to repair fractures and micro-damages. Despite bone's ability to heal spontaneously, certain situations require an additional stimulation of bone regeneration, such as non-union fractures or after tumor resection. Among the growth factors used to incr
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Klemmer, V. A., Khera, N., Siegenthaler, B. M., Bhattacharya, I., Weber, F. E., & Ghayor, C. (2021). Effect of N-Vinyl-2-Pyrrolidone (NVP), a Bromodomain-Binding Small Chemical, on Osteoblast and Osteoclast Differentiation and Its Potential Application for Bone Regeneration. International Journal of Molecular Sciences, 22(20), 11052. https://doi.org/10.3390/ijms222011052