Publication: Discovery of 42 genome-wide significant loci associated with dyslexia
Discovery of 42 genome-wide significant loci associated with dyslexia
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Doust, C., Fontanillas, P., Eising, E., et al, & Brandeis, D. (2022). Discovery of 42 genome-wide significant loci associated with dyslexia. Nature Genetics, 54, 1621–1629. https://doi.org/10.1038/s41588-022-01192-y
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Reading and writing are crucial life skills but roughly one in ten children are affected by dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up to 70%, yet few convincing genetic markers have been found. Here we performed a genome-wide association study of 51,800 adults self-reporting a dyslexia diagnosis and 1,087,070 controls and identified 42 independent genome-wide significant loci: 15 in genes linked to cognitive ability/educational attainment, and 27 new and potentially more specific to
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Doust, C., Fontanillas, P., Eising, E., et al, & Brandeis, D. (2022). Discovery of 42 genome-wide significant loci associated with dyslexia. Nature Genetics, 54, 1621–1629. https://doi.org/10.1038/s41588-022-01192-y
