Publication: Separation of collagen-bound and porous bone-water longitudinal relaxation in mice using a segmented inversion recovery zero-echo-time sequence
Separation of collagen-bound and porous bone-water longitudinal relaxation in mice using a segmented inversion recovery zero-echo-time sequence
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Marcon, M., Keller, D., Wurnig, M. C., Weiger, M., Kenkel, D., Eberhardt, C., Eberli, D., & Boss, A. (2017). Separation of collagen-bound and porous bone-water longitudinal relaxation in mice using a segmented inversion recovery zero-echo-time sequence. Magnetic Resonance in Medicine, 77(5), 1909–1915. https://doi.org/10.1002/mrm.26277
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PURPOSE: Cortical bone mechanical properties are related to the collagen-bound water (CBW) and pore water (PW) components of cortical bone. The study evaluates the feasibility of zero-echo-time imaging in mice in vivo for longitudinal relaxation time (T1) measurements in cortical bone and separation of CBW and PW components. METHODS: Zero-echo-time data were acquired at 4.7 Tesla in six mice with 14 different inversion times (0-2,600 ms). Region-of-interest analysis was performed at level of femur diaphysis. The T1 of cortical bone an
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- Marcon, Magda
- Keller, Daniel
- Wurnig, Moritz C
- Weiger, Markus
- Kenkel, David
- Eberhardt, Christian
- Eberli, Daniel
- Boss, Andreas
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Marcon, M., Keller, D., Wurnig, M. C., Weiger, M., Kenkel, D., Eberhardt, C., Eberli, D., & Boss, A. (2017). Separation of collagen-bound and porous bone-water longitudinal relaxation in mice using a segmented inversion recovery zero-echo-time sequence. Magnetic Resonance in Medicine, 77(5), 1909–1915. https://doi.org/10.1002/mrm.26277
