Lower core body temperature and greater body fat are components of a human thrifty phenotype

Abstract

BACKGROUND/OBJECTIVES In small studies, a thrifty human phenotype, defined by a greater 24-hour energy expenditure (EE) decrease with fasting, is associated with less weight loss during caloric restriction. In rodents, models of diet-induced obesity often have a phenotype including a reduced EE and decreased core body temperature. We assessed whether a thrifty human phenotype associates with differences in core body temperature or body composition. SUBJECTS/METHODS Data for this cross-sectional analysis were obtained from 77 indivi Show more