Publication: Measuring DNA Damage Using the Alkaline Comet Assay in Cultured Cells
Measuring DNA Damage Using the Alkaline Comet Assay in Cultured Cells
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Clementi, E., Garajova, Z., & Markkanen, E. (2021). Measuring DNA Damage Using the Alkaline Comet Assay in Cultured Cells. Bio-Protocol, 11(16), e4119. https://doi.org/10.21769/BioProtoc.4119
Abstract
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Abstract
Maintenance of DNA integrity is of pivotal importance for cells to circumvent detrimental processes that can ultimately lead to the development of various diseases. In the face of a plethora of endogenous and exogenous DNA-damaging agents, cells have evolved a variety of DNA repair mechanisms that are responsible for safeguarding genetic integrity. Given the relevance of DNA damage and its repair in disease, measuring the amount of both aspects is of considerable interest. The comet assay is a widely used method that allows the measur
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- Clementi, Elena
- Garajova, Zuzana
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Clementi, E., Garajova, Z., & Markkanen, E. (2021). Measuring DNA Damage Using the Alkaline Comet Assay in Cultured Cells. Bio-Protocol, 11(16), e4119. https://doi.org/10.21769/BioProtoc.4119
