Publication: Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints
Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints
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Cavedo, E., Chiesa, P. A., Houot, M., Ferretti, M. T., Grothe, M. J., Teipel, S. J., Lista, S., Habert, M.-O., Potier, M.-C., Dubois, B., & Hampel, H. (2018). Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer’s disease in cognitively normal older adults with subjective memory complaints. Alzheimer’s & Dementia, 14(9), 1204–1215. https://doi.org/10.1016/j.jalz.2018.05.014
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INTRODUCTION: Observational multimodal neuroimaging studies indicate sex differences in Alzheimer's disease pathophysiological markers. METHODS: Positron emission tomography brain amyloid load, neurodegeneration (hippocampus and basal forebrain volumes adjusted to total intracranial volume, cortical thickness, and 2-deoxy-2-[fluorine-18]fluoro-D-glucose-positron emission tomography metabolism), and brain resting-state functional connectivity were analyzed in 318 cognitively intact older adults from the INSIGHT-preAD cohort (female n =
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Cavedo, E., Chiesa, P. A., Houot, M., Ferretti, M. T., Grothe, M. J., Teipel, S. J., Lista, S., Habert, M.-O., Potier, M.-C., Dubois, B., & Hampel, H. (2018). Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer’s disease in cognitively normal older adults with subjective memory complaints. Alzheimer’s & Dementia, 14(9), 1204–1215. https://doi.org/10.1016/j.jalz.2018.05.014