Publication: Paraneoplastic tubulointerstitial nephritis exacerbated by immune checkpoint inhibitor
Paraneoplastic tubulointerstitial nephritis exacerbated by immune checkpoint inhibitor
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Scherer, T. P., Saba, K., Strebel, R. T., Gaspert, A., Cathomas, R., & Fehr, T. (2021). Paraneoplastic tubulointerstitial nephritis exacerbated by immune checkpoint inhibitor. Journal of Onco-Nephrology, 5(3), 195–199. https://doi.org/10.1177/23993693211056351
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Background: With the expanding indications and thus broader use of immune checkpoint inhibitors, clinicians are faced with a new kind of immune-related adverse events. Because of their immune modulating effects, immune checkpoint inhibitors have the potential to worsen autoimmunity in general. Paraneoplastic syndromes can be caused by tumor-induced autoimmune mechanisms. The use of immune-activating substances such as checkpoint inhibitors might lead to exacerbation of paraneoplastic syndromes causing premature discontinuation of the
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Scherer, T. P., Saba, K., Strebel, R. T., Gaspert, A., Cathomas, R., & Fehr, T. (2021). Paraneoplastic tubulointerstitial nephritis exacerbated by immune checkpoint inhibitor. Journal of Onco-Nephrology, 5(3), 195–199. https://doi.org/10.1177/23993693211056351
