Publication: Effect of APOE ɛ4 Status on Brain Amyloid-β and Cognitive Function in Amnestic and Nonamnestic Mild Cognitive Impairment: A 18F Florbetapir PET-CT Study
Effect of APOE ɛ4 Status on Brain Amyloid-β and Cognitive Function in Amnestic and Nonamnestic Mild Cognitive Impairment: A 18F Florbetapir PET-CT Study
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Wang, M., Zhang, Z., Wang, Y., Huang, L., Huang, Q., Ren, S., Qian, L., Ni, R., Guo, Q., Guan, Y., & Xie, F. (2024). Effect of APOE ɛ4 Status on Brain Amyloid-β and Cognitive Function in Amnestic and Nonamnestic Mild Cognitive Impairment: A 18F Florbetapir PET-CT Study. Advanced Therapeutics, 7, 2400008. https://doi.org/10.1002/adtp.202400008
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Mild cognitive impairment (MCI) is recognized as a predementia syndrome caused by multiple etiologies and nonmemory symptoms in MCI have recently gained increasing attention. However, the pattern of Aβ deposition and the effect of APOE (apolipoprotein E, APOE) ε4 on cognitive impairment in amnestic MCI (aMCI) and nonamnestic MCI (naMCI) patients has not been demonstrated. In this work, the amyloid-β (Aβ) load by [$^{18}$F]florbetapir PET imaging and cognitive performance is compared by comprehensive neuropsychological scales in partic
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Wang, M., Zhang, Z., Wang, Y., Huang, L., Huang, Q., Ren, S., Qian, L., Ni, R., Guo, Q., Guan, Y., & Xie, F. (2024). Effect of APOE ɛ4 Status on Brain Amyloid-β and Cognitive Function in Amnestic and Nonamnestic Mild Cognitive Impairment: A 18F Florbetapir PET-CT Study. Advanced Therapeutics, 7, 2400008. https://doi.org/10.1002/adtp.202400008