Publication: Drosophila DDX3/Belle exerts its function outside of the Wnt/Wingless signaling pathway
Drosophila DDX3/Belle exerts its function outside of the Wnt/Wingless signaling pathway
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Jenny, F. H., & Basler, K. (2016). Drosophila DDX3/Belle exerts its function outside of the Wnt/Wingless signaling pathway. PLoS ONE, 11(12), e0166862. https://doi.org/10.1371/journal.pone.0166862
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Abstract
The helicases human DDX3 and Drosophila Belle (Bel) are part of a well-defined subfamily of the DEAD-box helicases. Individual subfamily-members perform a myriad of functions in nuclear and cytosolic RNA metabolism. It has also been reported that DDX3X is involved in cell signaling, including IFN-α and IFN-β inducing pathways upon viral infection as well as in Wnt signaling. Here we used a collection of EMS-induced bel alleles recovered from a Wingless (Wg) suppressor screen to analyze the role of the Drosophila homolog of DDX3 in Wg/
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- Jenny, Fabian H
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Jenny, F. H., & Basler, K. (2016). Drosophila DDX3/Belle exerts its function outside of the Wnt/Wingless signaling pathway. PLoS ONE, 11(12), e0166862. https://doi.org/10.1371/journal.pone.0166862
