Publication: Better utilization of mouse models of neurodegenerative diseases in preclinical studies: from the bench to the clinic
Better utilization of mouse models of neurodegenerative diseases in preclinical studies: from the bench to the clinic
Date
Date
Date
Citations
Janus, C., Hernandez, C., deLelys, V., Roder, H., & Welzl, H. (2016). Better utilization of mouse models of neurodegenerative diseases in preclinical studies: from the bench to the clinic. In G. Proetzel & M. V. Wiles (Eds.), Mouse models for drug discovery: Methods and protocols (No. 1438; Vol. 1438, Issue 1438, pp. 311–347). Springer. https://doi.org/10.1007/978-1-4939-3661-8_18
Abstract
Abstract
Abstract
The major symptom of Alzheimer’s disease is dementia progressing with age. Its clinical diagnosis is preceded by a long prodromal period of brain pathology that encompasses both formation of extracellular amyloid and intraneuronal tau deposits in the brain and widespread neuronal death. At present, familial cases of dementia provide the most promising foundation for modeling neurodegenerative tauopathies, a group of heterogeneous disorders characterized by prominent intracellular accumulation of hyperphosphorylated tau protein. In thi
Additional indexing
Creators (Authors)
Editors
Title of Book
Title of Book
Title of Book
Place of Publication
Place of Publication
Place of Publication
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
Series Name
Series Name
Series Name
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
ISBN or e-ISBN
ISBN or e-ISBN
ISBN or e-ISBN
OA Status
OA Status
OA Status
Publisher DOI
Citations
Janus, C., Hernandez, C., deLelys, V., Roder, H., & Welzl, H. (2016). Better utilization of mouse models of neurodegenerative diseases in preclinical studies: from the bench to the clinic. In G. Proetzel & M. V. Wiles (Eds.), Mouse models for drug discovery: Methods and protocols (No. 1438; Vol. 1438, Issue 1438, pp. 311–347). Springer. https://doi.org/10.1007/978-1-4939-3661-8_18
