Publication: Characterization of the DNA copy-number genome in the blood of cutaneous T-cell lymphoma patients
Characterization of the DNA copy-number genome in the blood of cutaneous T-cell lymphoma patients
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Lin, W. M., Lewis, J. M., Filler, R. B., Modi, B. G., Carlson, K. R., Reddy, S., Thornberg, A., Saksena, G., Umlauf, S., Oberholzer, P. A., Karpova, M., Getz, G., Mane, S., Garraway, L. A., Dummer, R., Berger, C. L., Edelson, R. L., & Girardi, M. (2012). Characterization of the DNA copy-number genome in the blood of cutaneous T-cell lymphoma patients. Journal of Investigative Dermatology, 132, 188–197. https://doi.org/10.1038/jid.2011.254
Abstract
Abstract
Abstract
Cutaneous T-cell lymphoma (CTCL) is a heterogeneous non-Hodgkin's lymphoma that may variably involve the skin, lymph nodes, and peripheral blood. Malignant burden ranges from cutaneous patches and plaques with little evidence of blood involvement to erythroderma often in association with frank leukemia, as in Sézary syndrome. Toward a better understanding of the pathogenesis of this CD4+ T-cell malignancy, we conducted a high-resolution genomic analysis combining DNA (23 samples) and mRNA (12 samples) data of peripheral blood isolates
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Creators (Authors)
- Lin, W M
- Lewis, J M
- Filler, R B
- Modi, B G
- Carlson, K R
- Reddy, S
- Thornberg, A
- Saksena, G
- Umlauf, S
- Oberholzer, P A
- Karpova, M
- Getz, G
- Mane, S
- Garraway, L A
- Dummer, R
- Berger, C L
- Edelson, R L
- Girardi, M
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Citations
Lin, W. M., Lewis, J. M., Filler, R. B., Modi, B. G., Carlson, K. R., Reddy, S., Thornberg, A., Saksena, G., Umlauf, S., Oberholzer, P. A., Karpova, M., Getz, G., Mane, S., Garraway, L. A., Dummer, R., Berger, C. L., Edelson, R. L., & Girardi, M. (2012). Characterization of the DNA copy-number genome in the blood of cutaneous T-cell lymphoma patients. Journal of Investigative Dermatology, 132, 188–197. https://doi.org/10.1038/jid.2011.254
