Publication: Mechanisms of cellular rejuvenation
Mechanisms of cellular rejuvenation
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Denoth-Lippuner, A., & Jessberger, S. (2019). Mechanisms of cellular rejuvenation. FEBS Letters, 593, 3381–3392. https://doi.org/10.1002/1873-3468.13483
Abstract
Abstract
Abstract
Aging leads to changes on an organismal but also cellular level. However, the exact mechanisms of cellular aging in mammals remain poorly understood and the identity and functional role of aging factors, some of which have previously been defined in model organisms such as Saccharomyces cerevisiae, remain elusive. Remarkably, during cellular reprogramming most if not all aging hallmarks are erased, offering a novel entry point to study aging and rejuvenation on a cellular level. On the other hand, direct reprogramming of old cells int
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- Denoth-Lippuner, Annina
- Jessberger, Sebastian
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Citations
Denoth-Lippuner, A., & Jessberger, S. (2019). Mechanisms of cellular rejuvenation. FEBS Letters, 593, 3381–3392. https://doi.org/10.1002/1873-3468.13483