Publication: Quantitative analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography
Quantitative analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography
Date
Date
Date
Citations
Eltsov, M., Dubé, N., Yu, Z., Pasakarnis, L., Haselmann-Weiss, U., Brunner, D., & Frangakis, A. S. (2015). Quantitative analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography. Nature Cell Biology, 17(5), 605–614. https://doi.org/10.1038/ncb3159
Abstract
Abstract
Abstract
The closure of epidermal openings is an essential biological process that causes major developmental problems such as spina bifida in humans if it goes awry. At present, the mechanism of closure remains elusive. Therefore, we reconstructed a model closure event, dorsal closure in fly embryos, by large-volume correlative electron tomography. We present a comprehensive, quantitative analysis of the cytoskeletal reorganization, enabling separated epidermal cells to seal the epithelium. After establishing contact through actin-driven expl
Additional indexing
Creators (Authors)
- Eltsov, Mikhail
- Dubé, Nadia
- Yu, Zhou
- Pasakarnis, Laurynas
- Haselmann-Weiss, Uta
- Brunner, Damian
- Frangakis, Achilleas S
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
In collections
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Publisher DOI
Citations
Eltsov, M., Dubé, N., Yu, Z., Pasakarnis, L., Haselmann-Weiss, U., Brunner, D., & Frangakis, A. S. (2015). Quantitative analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography. Nature Cell Biology, 17(5), 605–614. https://doi.org/10.1038/ncb3159
