Publication: Random number generation deficits in patients with multiple sclerosis: Characteristics and neural correlates
Random number generation deficits in patients with multiple sclerosis: Characteristics and neural correlates
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Geisseler, O., Pflugshaupt, T., Buchmann, A., Bezzola, L., Reuter, K., Schuknecht, B., Weller, D., Linnebank, M., & Brugger, P. (2016). Random number generation deficits in patients with multiple sclerosis: Characteristics and neural correlates. Cortex, 82, 237–243. https://doi.org/10.1016/j.cortex.2016.05.007
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Human subjects typically deviate systematically from randomness when attempting to produce a sequence of random numbers. Despite an increasing number of behavioral and functional neuroimaging studies on random number generation (RNG), its structural correlates have never been investigated. We set out to fill this gap in 44 patients with multiple sclerosis (MS), a disease whose impact on RNG has never been studied. The RNG task required the paced (1 Hz) generation of the numbers from 1 to 6 in a sequence as random as possible. The same
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Geisseler, O., Pflugshaupt, T., Buchmann, A., Bezzola, L., Reuter, K., Schuknecht, B., Weller, D., Linnebank, M., & Brugger, P. (2016). Random number generation deficits in patients with multiple sclerosis: Characteristics and neural correlates. Cortex, 82, 237–243. https://doi.org/10.1016/j.cortex.2016.05.007