High prevalence of extended-spectrum ß-lactamase producing Enterobacteriaceae among clinical isolates from cats and dogs admitted to a Veterinary Hospital in Switzerland

Zogg, Anna Lena; Simmen, Sabrina; Zurfluh, Katrin; Stephan, Roger; Schmitt, Sarah N; Nüesch-Inderbinen, Magdalena

doi:10.3389/fvets.2018.00062

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Zogg, A. L., Simmen, S., Zurfluh, K., Stephan, R., Schmitt, S. N., & Nüesch-Inderbinen, M. (2018). High prevalence of extended-spectrum ß-lactamase producing Enterobacteriaceae among clinical isolates from cats and dogs admitted to a Veterinary Hospital in Switzerland. Frontiers in Veterinary Science, 5, 62. https://doi.org/10.3389/fvets.2018.00062

Abstract

Objectives: This study aimed to identify and characterize extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae among clinical samples of companion animals. Methods: A total of 346 non-duplicate Enterobacteriaceae isolates were collected between 2012 and 2016 from diseased cats (n = 115) and dogs (n = 231). The presence of blaESBL, PMQR genes, and the azithromycin resistance gene mph(A) was confirmed by PCR and sequencing of bla genes. Isolates were further characterized by antimicrobial resistance profiling, multilocus se