Publication: Uterine extracellular vesicles as multi-signal messengers during maternal recognition of pregnancy in the mare
Uterine extracellular vesicles as multi-signal messengers during maternal recognition of pregnancy in the mare
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Rudolf Vegas, A., Hamdi, M., Podico, G., Bollwein, H., Fröhlich, T., Canisso, I. F., Bauersachs, S., & Almiñana, C. (2022). Uterine extracellular vesicles as multi-signal messengers during maternal recognition of pregnancy in the mare. Scientific Reports, 12(1), 15616. https://doi.org/10.1038/s41598-022-19958-z
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In contrast to other domestic mammals, the embryo-derived signal(s) leading to maternal recognition of pregnancy (MRP) are still unknow in the mare. We hypothesize that these embryonic signals could be packed into uterine extracellular vesicles (uEVs), acting as multi-signal messengers between the conceptus and the maternal tract, and contributing to MRP. To unveil these signals, the RNA and protein cargos of uEVs isolated from uterine lavages collected from pregnant mares (P; day 10, 11, 12 and 13 after ovulation) and cyclic control
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Rudolf Vegas, A., Hamdi, M., Podico, G., Bollwein, H., Fröhlich, T., Canisso, I. F., Bauersachs, S., & Almiñana, C. (2022). Uterine extracellular vesicles as multi-signal messengers during maternal recognition of pregnancy in the mare. Scientific Reports, 12(1), 15616. https://doi.org/10.1038/s41598-022-19958-z
