Publication: Practical Application of the 3Rs in Rodent Transgenesis
Practical Application of the 3Rs in Rodent Transgenesis
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Buch, T., Jerchow, B., & Zevnik, B. (2023). Practical Application of the 3Rs in Rodent Transgenesis. Practical Application of the 3Rs in Rodent Transgenesis, 2631, 33–51. https://doi.org/10.1007/978-1-0716-2990-1_2
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The principles of the 3Rs (replace, reduce, refine), as originally published by Russell and Burch, are internationally acclaimed guidelines for meeting ethical and welfare standards in animal experimentation. Genome manipulation is a standard technique in biomedical research and beyond. The goal of this chapter is to give practical advice on the implementation of the 3Rs in laboratories generating genetically modified rodents. We cover 3R aspects from the planning phase through operations of the transgenic unit to the final genome-man
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- Jerchow, Boris
- Zevnik, Branko
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Buch, T., Jerchow, B., & Zevnik, B. (2023). Practical Application of the 3Rs in Rodent Transgenesis. Practical Application of the 3Rs in Rodent Transgenesis, 2631, 33–51. https://doi.org/10.1007/978-1-0716-2990-1_2
