Publication: Real-world stress resilience is associated with the responsivity of the locus coeruleus
Real-world stress resilience is associated with the responsivity of the locus coeruleus
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Grueschow, M., Stenz, N., Thörn, H., Ehlert, U., Breckwoldt, J., Brodmann Maeder, M., Exadaktylos, A. K., Bingisser, R., Ruff, C. C., & Kleim, B. (2021). Real-world stress resilience is associated with the responsivity of the locus coeruleus. Nature Communications, 12(1), 2275. https://doi.org/10.1038/s41467-021-22509-1
Abstract
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Abstract
Individuals may show different responses to stressful events. Here, we investigate the neurobiological basis of stress resilience, by showing that neural responsitivity of the noradrenergic locus coeruleus (LC-NE) and associated pupil responses are related to the subsequent change in measures of anxiety and depression in response to prolonged real-life stress. We acquired fMRI and pupillometry data during an emotional-conflict task in medical residents before they underwent stressful emergency-room internships known to be a risk facto
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- Stenz, Nico
- Thörn, Hanna
- Ehlert, Ulrike
- Brodmann Maeder, Monika
- Exadaktylos, Aristomenis K
- Bingisser, Roland
- Kleim, Birgit
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Grueschow, M., Stenz, N., Thörn, H., Ehlert, U., Breckwoldt, J., Brodmann Maeder, M., Exadaktylos, A. K., Bingisser, R., Ruff, C. C., & Kleim, B. (2021). Real-world stress resilience is associated with the responsivity of the locus coeruleus. Nature Communications, 12(1), 2275. https://doi.org/10.1038/s41467-021-22509-1
