Publication: Speed of cooling after cardiac arrest in relation to the intervention effect: a sub-study from the TTM2-trial
Speed of cooling after cardiac arrest in relation to the intervention effect: a sub-study from the TTM2-trial
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Simpson, R. F. G., Dankiewicz, J., Karamasis, G. V., Pelosi, P., Haenggi, M., Young, P. J., Jakobsen, J. C., Bannard-Smith, J., Wendel-Garcia, P. D., Taccone, F. S., Nordberg, P., Wise, M. P., Grejs, A. M., Lilja, G., Olsen, R. B., Cariou, A., Lascarrou, J. B., Saxena, M., Hovdenes, J., … Keeble, T. R. (2022). Speed of cooling after cardiac arrest in relation to the intervention effect: a sub-study from the TTM2-trial. Critical Care, 26, 356. https://doi.org/10.1186/s13054-022-04231-6
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Background: Targeted temperature management (TTM) is recommended following cardiac arrest; however, time to target temperature varies in clinical practice. We hypothesised the effects of a target temperature of 33 °C when compared to normothermia would differ based on average time to hypothermia and those patients achieving hypothermia fastest would have more favorable outcomes.
Methods: In this post-hoc analysis of the TTM-2 trial, patients after out of hospital cardiac arrest were randomized to targeted hypothermia (33 °C), followe
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Simpson, R. F. G., Dankiewicz, J., Karamasis, G. V., Pelosi, P., Haenggi, M., Young, P. J., Jakobsen, J. C., Bannard-Smith, J., Wendel-Garcia, P. D., Taccone, F. S., Nordberg, P., Wise, M. P., Grejs, A. M., Lilja, G., Olsen, R. B., Cariou, A., Lascarrou, J. B., Saxena, M., Hovdenes, J., … Keeble, T. R. (2022). Speed of cooling after cardiac arrest in relation to the intervention effect: a sub-study from the TTM2-trial. Critical Care, 26, 356. https://doi.org/10.1186/s13054-022-04231-6
