Publication: Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study
Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study
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Zürcher, K., Reichmuth, M. L., Ballif, M., Loiseau, C., Borrell, S., Reinhard, M., Skrivankova, V., Hömke, R., Sander, P., Avihingsanon, A., Abimiku, A. G., Marcy, O., Collantes, J., Carter, E. J., Wilkinson, R. J., Cox, H., Yotebieng, M., Huebner, R., Fenner, L., … Egger, M. (2021). Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study. The Lancet Microbe, 2(7), e320–e330. https://doi.org/10.1016/S2666-5247(21)00044-6
Abstract
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Background
Drug resistance threatens global tuberculosis control. We aimed to examine mortality in patients with tuberculosis from high-burden countries, according to concordance or discordance of results from drug susceptibility testing done locally and whole-genome sequencing (WGS). Methods
In this multicentre cohort study, we collected pulmonary Mycobacterium tuberculosis isolates and clinical data from individuals with tuberculosis from antiretroviral therapy programmes and tuberculosis clinics in Côte d'Ivoire, Democratic Repub
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Creators (Authors)
- Zürcher, K
- Reichmuth, M L
- Ballif, M
- Loiseau, C
- Borrell, S
- Reinhard, M
- Skrivankova, V
- Hömke, R
- Sander, P
- Avihingsanon, A
- Abimiku, A G
- Marcy, O
- Collantes, J
- Carter, E Jane
- Wilkinson, R J
- Cox, H
- Yotebieng, M
- Huebner, R
- Fenner, L
- Böttger, E C
- Gagneux, S
- Egger, M
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Zürcher, K., Reichmuth, M. L., Ballif, M., Loiseau, C., Borrell, S., Reinhard, M., Skrivankova, V., Hömke, R., Sander, P., Avihingsanon, A., Abimiku, A. G., Marcy, O., Collantes, J., Carter, E. J., Wilkinson, R. J., Cox, H., Yotebieng, M., Huebner, R., Fenner, L., … Egger, M. (2021). Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study. The Lancet Microbe, 2(7), e320–e330. https://doi.org/10.1016/S2666-5247(21)00044-6
