Publication: Drosophila β-Tubulin 97EF is upregulated at low temperature and stabilizes microtubules
Drosophila β-Tubulin 97EF is upregulated at low temperature and stabilizes microtubules
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Myachina, F., Bosshardt, F., Bischof, J., Kirschmann, M., & Lehner, C. F. (2017). Drosophila β-Tubulin 97EF is upregulated at low temperature and stabilizes microtubules. Development, 144(24), 4573–4587. https://doi.org/10.1242/dev.156109
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Cells in ectotherms function normally within an often wide temperature range. As temperature dependence is not uniform across all the distinct biological processes, acclimation presumably requires complex regulation. The molecular mechanisms that cope with the disruptive effects of temperature variation are still poorly understood. Interestingly, one of five different β-tubulin paralogs, βTub97EF, was among the genes upregulated at low temperature in cultured Drosophila cells. As microtubules are known to be cold sensitive, we analyze
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Myachina, F., Bosshardt, F., Bischof, J., Kirschmann, M., & Lehner, C. F. (2017). Drosophila β-Tubulin 97EF is upregulated at low temperature and stabilizes microtubules. Development, 144(24), 4573–4587. https://doi.org/10.1242/dev.156109