Exploring the potential of silica mixed zinc phosphate bioactive glasses for bone regeneration: In vitro bioactivity and antibacterial activity analysis

Babu, M Mohan; Bhemarajam, J; Lakshmi, A Maha; Murimadugula, Sathaiah; Devi, T Indira; Sroda, M; Özcan, Mutlu; Rao, P Venkateswara; Prasad, P Syam

doi:10.1016/j.jnoncrysol.2023.122639

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Babu, M. M., Bhemarajam, J., Lakshmi, A. M., Murimadugula, S., Devi, T. I., Sroda, M., Özcan, M., Rao, P. V., & Prasad, P. S. (2023). Exploring the potential of silica mixed zinc phosphate bioactive glasses for bone regeneration: In vitro bioactivity and antibacterial activity analysis. Journal of Non-Crystalline Solids, 622, 122639. https://doi.org/10.1016/j.jnoncrysol.2023.122639

Abstract

Biomaterials development is currently the main active research area in the field of bone tissue engineering. In the present study, the bioactive glasses with different chemical compositions (mol %) of zinc oxide, silica, calcium oxide, sodium oxide, and phosphates were synthesized by the melt-quench technique. We studied the thermal, physical, and other structural characteristics of the glasses to know the structural stability and potentiality to use as implant material. The in-vitro studies were performed to test the apatite forming