Publication: Functions of Nogo-A in the Innervation and Mineralisation of Rodent Teeth
Functions of Nogo-A in the Innervation and Mineralisation of Rodent Teeth
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Pirenne, L. (2024). Functions of Nogo-A in the Innervation and Mineralisation of Rodent Teeth. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-259617
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Nogo-A is best described as an inhibitor of axon regeneration in the adult central nervous system (CNS). At the cell surface, Nogo-A signals through receptor complexes to trigger the disorganisation of the cytoskeleton and the downregulation of growth-related genes. Blocking Nogo-A treatments have since been developed into human clinical trials for CNS regeneration. Nogo-A is also involved in the development and physiology of the CNS. Furthermore, its expression and functions extend beyond neuronal tissues. Indeed, Nogo-A regulates di
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Pirenne, L. (2024). Functions of Nogo-A in the Innervation and Mineralisation of Rodent Teeth. (Dissertation, University of Zurich) https://doi.org/10.5167/uzh-259617