Publication: Feasibility of glioblastoma tissue response mapping with physiologic BOLD imaging using precise oxygen and carbon dioxide challenge
Feasibility of glioblastoma tissue response mapping with physiologic BOLD imaging using precise oxygen and carbon dioxide challenge
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Stumpo, V., Sebök, M., van Niftrik, C. H. B., Seystahl, K., Hainc, N., Kulcsar, Z., Weller, M., Regli, L., & Fierstra, J. (2022). Feasibility of glioblastoma tissue response mapping with physiologic BOLD imaging using precise oxygen and carbon dioxide challenge. Magma, 35(1), 29–44. https://doi.org/10.1007/s10334-021-00980-7
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Objectives: Innovative physiologic MRI development focuses on depiction of heterogenous vascular and metabolic features in glioblastoma. For this feasibility study, we employed blood oxygenation level-dependent (BOLD) MRI with standardized and precise carbon dioxide (CO2) and oxygen (O2) modulation to investigate specific tumor tissue response patterns in patients with newly diagnosed glioblastoma.
Materials and methods: Seven newly diagnosed untreated patients with suspected glioblastoma were prospectively included to undergo a BOLD
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Stumpo, V., Sebök, M., van Niftrik, C. H. B., Seystahl, K., Hainc, N., Kulcsar, Z., Weller, M., Regli, L., & Fierstra, J. (2022). Feasibility of glioblastoma tissue response mapping with physiologic BOLD imaging using precise oxygen and carbon dioxide challenge. Magma, 35(1), 29–44. https://doi.org/10.1007/s10334-021-00980-7
