Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort

Wendel Garcia, Pedro David; Fumeaux, Thierry; Guerci, Philippe; Heuberger, Dorothea Monika; Montomoli, Jonathan; Roche-Campo, Ferran; Schuepbach, Reto Andreas; Hilty, Matthias Peter

doi:10.1016/j.eclinm.2020.100449

Citations

Citation copied

Wendel Garcia, P. D., Fumeaux, T., Guerci, P., Heuberger, D. M., Montomoli, J., Roche-Campo, F., Schuepbach, R. A., & Hilty, M. P. (2020). Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort. EClinicalMedicine, 25, 100449. https://doi.org/10.1016/j.eclinm.2020.100449

Abstract

Background

Coronavirus disease 2019 (COVID-19) is associated with a high disease burden with 10% of confirmed cases progressing towards critical illness. Nevertheless, the disease course and predictors of mortality in critically ill patients are poorly understood. Methods

Following the critical developments in ICUs in regions experiencing early inception of the pandemic, the European-based, international RIsk Stratification in COVID-19 patients in the Intensive Care Unit (RISC-19-ICU) registry was created to provide near real-time a