Publication: Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study
Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study
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Durrenberger, P. F., Fernando, F. S., Kashefi, S. N., Bonnert, T. P., Seilhean, D., Nait-Oumesmar, B., Schmitt, A., Gebicke-Haerter, P. J., Falkai, P., Grünblatt, E., Palkovits, M., Arzberger, T., Kretzschmar, H., Dexter, D. T., & Reynolds, R. (2015). Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study. Journal of Neural Transmission, 122(7), 1055–1068. https://doi.org/10.1007/s00702-014-1293-0
Abstract
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Abstract
Neurodegenerative diseases of the central nervous system are characterized by pathogenetic cellular and molecular changes in specific areas of the brain that lead to the dysfunction and/or loss of explicit neuronal populations. Despite exhibiting different clinical profiles and selective neuronal loss, common features such as abnormal protein deposition, dysfunctional cellular transport, mitochondrial deficits, glutamate excitotoxicity, iron accumulation and inflammation are observed in many neurodegenerative disorders, suggesting con
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Creators (Authors)
- Durrenberger, Pascal F
- Fernando, Francesca S
- Kashefi, Samira N
- Bonnert, Tim P
- Seilhean, Danielle
- Nait-Oumesmar, Brahim
- Schmitt, Andrea
- Gebicke-Haerter, Peter J
- Falkai, Peter
- Grünblatt, Edna
- Palkovits, Miklos
- Arzberger, Thomas
- Kretzschmar, Hans
- Dexter, David T
- Reynolds, Richard
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Durrenberger, P. F., Fernando, F. S., Kashefi, S. N., Bonnert, T. P., Seilhean, D., Nait-Oumesmar, B., Schmitt, A., Gebicke-Haerter, P. J., Falkai, P., Grünblatt, E., Palkovits, M., Arzberger, T., Kretzschmar, H., Dexter, D. T., & Reynolds, R. (2015). Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study. Journal of Neural Transmission, 122(7), 1055–1068. https://doi.org/10.1007/s00702-014-1293-0
