Publication: Radiation-induced lymphopenia does not impact treatment efficacy in a mouse tumor model
Radiation-induced lymphopenia does not impact treatment efficacy in a mouse tumor model
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Telarovic, I., Yong, C. S. M., Guckenberger, M., Unkelbach, J., & Pruschy, M. (2022). Radiation-induced lymphopenia does not impact treatment efficacy in a mouse tumor model. Neoplasia, 31, 100812. https://doi.org/10.1016/j.neo.2022.100812
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Abstract
Radiation-induced lymphopenia is a common occurrence in radiation oncology and an established negative prognostic factor, however the mechanisms underlying the relationship between lymphopenia and inferior survival remain elusive. The relevance of lymphocyte co-irradiation as critical normal tissue component at risk is an emerging topic of high clinical relevance, even more so in the context of potentially synergistic radiotherapy-immunotherapy combinations. The impact of the radiotherapy treatment volume on the lymphocytes of healthy
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- Yong, Carmen S M
- Guckenberger, Matthias
- Unkelbach, Jan
- Pruschy, Martin
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Telarovic, I., Yong, C. S. M., Guckenberger, M., Unkelbach, J., & Pruschy, M. (2022). Radiation-induced lymphopenia does not impact treatment efficacy in a mouse tumor model. Neoplasia, 31, 100812. https://doi.org/10.1016/j.neo.2022.100812
