The impact of shock wave therapy at varied energy and dose levels on functional and structural changes in erectile tissue

Müller, A; Akin-Olugbade, Y; Deveci, S; Donohue, J F; Tal, R; Kobylarz, K A; Palese, M; Mulhall, J P

doi:10.1016/j.eururo.2007.06.032

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Müller, A., Akin-Olugbade, Y., Deveci, S., Donohue, J. F., Tal, R., Kobylarz, K. A., Palese, M., & Mulhall, J. P. (2008). The impact of shock wave therapy at varied energy and dose levels on functional and structural changes in erectile tissue. European Urology, 53(3), 635–643. https://doi.org/10.1016/j.eururo.2007.06.032

Abstract

OBJECTIVES: Only minimal literature exists on consequences of shock wave therapy (SWT) on erectile function in treatment of Peyronie's disease (PD). This study was undertaken to define SWT impact at varied energy/dose levels at different time points on functional and structural changes in erectile tissue. METHODS: In 45 rats 2000 shock waves (sw) at 2 BAR were applied to the penis weekly sorted by one, two, and three sessions (high-dose/energy level, HD-1, HD-2, HD-3). Each group was followed for 1, 7, or 28 d before measuring intraca