Publication: Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders
Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders
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Dutan Polit, L., Eidhof, I., McNeill, R. V., Warre-Cornish, K. M., Yde Ohki, C. M., Walter, N. M., Sala, C., Verpelli, C., Radtke, F., Galderisi, S., Mucci, A., Collo, G., Edenhofer, F., Castrén, M. L., Réthelyi, J. M., Ejlersen, M., Hohmann, S. S., Ilieva, M. S., Lukjanska, R., … et al. (2023). Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders. Neuroscience Applied, 2, 101125. https://doi.org/10.1016/j.nsa.2023.101125
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The number of individuals suffering from neuropsychiatric disorders (NPDs) has increased worldwide, with 3 million disability-adjusted life-years calculated in 2019. Though research using various approaches including genetics, imaging, clinical and animal models has advanced our knowledge regarding NPDs, we still lack basic knowledge regarding the underlying pathophysiological mechanisms. Moreover, there is an urgent need for highly effective therapeutics for NPDs. Human induced pluripotent stem cells (hiPSCs) generated from somatic c
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Dutan Polit, L., Eidhof, I., McNeill, R. V., Warre-Cornish, K. M., Yde Ohki, C. M., Walter, N. M., Sala, C., Verpelli, C., Radtke, F., Galderisi, S., Mucci, A., Collo, G., Edenhofer, F., Castrén, M. L., Réthelyi, J. M., Ejlersen, M., Hohmann, S. S., Ilieva, M. S., Lukjanska, R., … et al. (2023). Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders. Neuroscience Applied, 2, 101125. https://doi.org/10.1016/j.nsa.2023.101125
