Publication: Peripheral blood levels of matrix metalloproteinase-9 predict lesion volume in acute stroke
Peripheral blood levels of matrix metalloproteinase-9 predict lesion volume in acute stroke
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Ulrich, N. H., Dehmel, T., Wittsack, H. J., Kieseier, B. C., & Seitz, R. J. (2013). Peripheral blood levels of matrix metalloproteinase-9 predict lesion volume in acute stroke. Neurological Sciences, 34, 379–382. https://doi.org/10.1007/s10072-012-0999-8
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Matrix metalloproteinases (MMPs) have been implicated to play an important role in the destruction of the extracellular matrix in diseases of the central nervous system. This study investigated whether the expression of one of these proteases, MMP-9 in blood, is related to the size of human brain infarcts assessed with magnetic resonance imaging. Consecutively, twenty-one acute stroke patients were included prospectively into our study. In blood samples drawn within 24h after onset, MMP-9 RNA-expression and proteolytic-activity were a
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- Ulrich, Nils H
- Dehmel, T
- Wittsack, H J
- Kieseier, B C
- Seitz, R J
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Ulrich, N. H., Dehmel, T., Wittsack, H. J., Kieseier, B. C., & Seitz, R. J. (2013). Peripheral blood levels of matrix metalloproteinase-9 predict lesion volume in acute stroke. Neurological Sciences, 34, 379–382. https://doi.org/10.1007/s10072-012-0999-8
