Publication: In situ structural analysis of the Yersinia enterocolitica injectisome
In situ structural analysis of the Yersinia enterocolitica injectisome
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Kudryashev, M., Stenta, M., Schmelz, S., Amstutz, M., Wiesand, U., Castano-Diez, D., Degiacomi, M. T., Munnich, S., Bleck, C. K., Kowal, J., Diepold, A., Heinz, D. W., Dal Peraro, M., Cornelis, G. R., & Stahlberg, H. (2013). In situ structural analysis of the Yersinia enterocolitica injectisome. ELife, 2, e00792–e00792. https://doi.org/10.7554/eLife.00792
Abstract
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Abstract
Injectisomes are multi-protein transmembrane machines allowing pathogenic bacteria to inject effector proteins into eukaryotic host cells, a process called type III secretion. Here we present the first three-dimensional structure of Yersinia enterocolitica and Shigella flexneri injectisomes in situ and the first structural analysis of the Yersinia injectisome. Unexpectedly, basal bodies of injectisomes inside the bacterial cells showed length variations of 20%. The in situ structures of the Y. enterocolitica and S. flexneri injectisom
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- Kudryashev, M
- Stenta, M
- Schmelz, S
- Amstutz, M
- Wiesand, U
- Castano-Diez, D
- Degiacomi, M T
- Munnich, S
- Kowal, J
- Diepold, A
- Heinz, D W
- Dal Peraro, M
- Cornelis, G R
- Stahlberg, H
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Kudryashev, M., Stenta, M., Schmelz, S., Amstutz, M., Wiesand, U., Castano-Diez, D., Degiacomi, M. T., Munnich, S., Bleck, C. K., Kowal, J., Diepold, A., Heinz, D. W., Dal Peraro, M., Cornelis, G. R., & Stahlberg, H. (2013). In situ structural analysis of the Yersinia enterocolitica injectisome. ELife, 2, e00792–e00792. https://doi.org/10.7554/eLife.00792
