Publication: Biodegradable sleeves for metal implants to prevent implant-associated infection: an experimental in vivo study in sheep
Biodegradable sleeves for metal implants to prevent implant-associated infection: an experimental in vivo study in sheep
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von Plocki, S. C., Armbruster, D., Klein, K., Kämpf, K., Zlinszky, K., Hilbe, M., Kronen, P., Gruskin, E., & von Rechenberg, B. (2012). Biodegradable sleeves for metal implants to prevent implant-associated infection: an experimental in vivo study in sheep. Veterinary Surgery, 41(3), 410–421. https://doi.org/10.1111/j.1532-950X.2011.00943.x
Abstract
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OBJECTIVE: To evaluate biocompatibility of biodegradable sleeves containing antimicrobial agents, designed for local drug delivery to prevent implant-related infection. STUDY DESIGN: Synthetic polyester sleeves (a copolymer of glycolide, caprolactone, trimethylene carbonate, lactide) were cast as thin films. The antimicrobial agents incorporated in the sleeves included gentamicin sulfate, triclosan, or a combination of these drugs. ANIMALS: Adult sheep (n = 15). METHODS: Two limited contact dynamic compression plates (LC-DCP) with or
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- von Plocki, S C
- Armbruster, D
- Klein, K
- Kämpf, K
- Zlinszky, K
- Hilbe, Monika
- Kronen, P
- Gruskin, E
- von Rechenberg, Brigitte
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von Plocki, S. C., Armbruster, D., Klein, K., Kämpf, K., Zlinszky, K., Hilbe, M., Kronen, P., Gruskin, E., & von Rechenberg, B. (2012). Biodegradable sleeves for metal implants to prevent implant-associated infection: an experimental in vivo study in sheep. Veterinary Surgery, 41(3), 410–421. https://doi.org/10.1111/j.1532-950X.2011.00943.x
