Publication: A novel 5x multiplex immunohistochemical staining reveals PSMA as a helpful marker in prostate cancer with low p504s expression
A novel 5x multiplex immunohistochemical staining reveals PSMA as a helpful marker in prostate cancer with low p504s expression
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Rüschoff, J. H., Stratton, S., Roberts, E., Clark, S., Sebastiao, N., Fankhauser, C. D., Eberli, D., Moch, H., Wild, P. J., & Rupp, N. J. (2021). A novel 5x multiplex immunohistochemical staining reveals PSMA as a helpful marker in prostate cancer with low p504s expression. Pathology, Research and Practice, 228, 153667. https://doi.org/10.1016/j.prp.2021.153667
Abstract
Abstract
Abstract
The ability to combine multiple immunohistochemical (IHC) markers within a single tissue section facilitates the evaluation and detection of co-expressions, while saving tissue. A newly developed 5x multiplex (MPX) IHC staining of five different IHC markers (Basal cell cocktail (34βE12 + p63), p504s (SP116), ERG (EPR3864), Ki-67 (30-9), PSMA (EP192)) was applied on whole sections of n = 37 radical prostatectomies (RPE) including normal and cancerous tissue. Four different colors including brown, magenta, yellow and teal coded for diff
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Creators (Authors)
- Rüschoff, Jan H
- Stratton, Steven
- Roberts, Esteban
- Clark, Samantha
- Sebastiao, Noemi
- Fankhauser, Christian D
- Eberli, Daniel
- Moch, Holger
- Wild, Peter J
- Rupp, Niels J
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Citations
Rüschoff, J. H., Stratton, S., Roberts, E., Clark, S., Sebastiao, N., Fankhauser, C. D., Eberli, D., Moch, H., Wild, P. J., & Rupp, N. J. (2021). A novel 5x multiplex immunohistochemical staining reveals PSMA as a helpful marker in prostate cancer with low p504s expression. Pathology, Research and Practice, 228, 153667. https://doi.org/10.1016/j.prp.2021.153667
