Publication: Drug-induced liver injury: recent advances in diagnosis and risk assessment
Drug-induced liver injury: recent advances in diagnosis and risk assessment
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Kullak-Ublick, G. A., Andrade, R. J., Merz, M., End, P., Benesic, A., Gerbes, A. L., & Aithal, G. P. (2017). Drug-induced liver injury: recent advances in diagnosis and risk assessment. Gut, 66(6), 1154–1164. https://doi.org/10.1136/gutjnl-2016-313369
Abstract
Abstract
Abstract
Idiosyncratic drug-induced liver injury (IDILI) is a rare but potentially severe adverse drug reaction that should be considered in patients who develop laboratory criteria for liver injury secondary to the administration of a potentially hepatotoxic drug. Although currently used liver parameters are sensitive in detecting DILI, they are neither specific nor able to predict the patient's subsequent clinical course. Genetic risk assessment is useful mainly due to its high negative predictive value, with several human leucocyte antigen
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Creators (Authors)
- Kullak-Ublick, Gerd A
- Andrade, Raul J
- Merz, Michael
- End, Peter
- Benesic, Andreas
- Gerbes, Alexander L
- Aithal, Guruprasad P
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Kullak-Ublick, G. A., Andrade, R. J., Merz, M., End, P., Benesic, A., Gerbes, A. L., & Aithal, G. P. (2017). Drug-induced liver injury: recent advances in diagnosis and risk assessment. Gut, 66(6), 1154–1164. https://doi.org/10.1136/gutjnl-2016-313369
