Publication: Effects of oral antibiotics and isotretinoin on the murine gut microbiota
Effects of oral antibiotics and isotretinoin on the murine gut microbiota
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Becker, E., Schmidt, T. S. B., Bengs, S., Poveda, L., Opitz, L., Atrott, K., Stanzel, C., Biedermann, L., Rehman, A., Jonas, D., von Mering, C., Rogler, G., & Frey-Wagner, I. (2017). Effects of oral antibiotics and isotretinoin on the murine gut microbiota. International Journal of Antimicrobial Agents, 50(3), 342–351. https://doi.org/10.1016/j.ijantimicag.2017.03.017
Abstract
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Abstract
Inflammatory bowel disease (IBD) may develop due to an immunogenic response to commensal gut microbiota triggered by environmental factors in the genetically susceptible host. Isotretinoin, applied in the treatment of severe acne, has been variably associated with IBD, but prior treatment with antibiotics, also associated with IBD development, confounds confirmation of this association. This study investigated the effects of doxycycline, metronidazole (frequently used in the treatment of acne and IBD, respectively) and isotretinoin on
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Creators (Authors)
- Becker, Eugenia
- Schmidt, Thomas S B
- Bengs, Susan
- Poveda, Lucy
- Opitz, Lennart
- Atrott, Kirstin
- Stanzel, Claudia
- Biedermann, Luc
- Rehman, Ateequr
- Jonas, Daniel
- von Mering, Christian
- Rogler, Gerhard
- Frey-Wagner, Isabelle
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Citations
Becker, E., Schmidt, T. S. B., Bengs, S., Poveda, L., Opitz, L., Atrott, K., Stanzel, C., Biedermann, L., Rehman, A., Jonas, D., von Mering, C., Rogler, G., & Frey-Wagner, I. (2017). Effects of oral antibiotics and isotretinoin on the murine gut microbiota. International Journal of Antimicrobial Agents, 50(3), 342–351. https://doi.org/10.1016/j.ijantimicag.2017.03.017
