Publication: Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney
Date
Date
Date
2015
Journal Article
Published version
Abstract
Abstract
Abstract
The Rab GTPase-activating protein TBC1D4 (AS160) controls trafficking of the glucose transporter GLUT4 in adipocytes and skeletal muscle cells. TBC1D4 is also highly abundant in the renal distal tubule, although its role in this tubule is so far unknown. In vitro studies suggest that it is involved in the regulation of renal transporters and channels such as the epithelial sodium channel (ENaC), aquaporin-2 (AQP2), and the Na(+)-K(+)-ATPase. To assess the physiological role of TBC1D4 in the kidney, wild-type (TBC1D4(+/+)) and TBC1D4-d
Metrics
Views
184 since deposited on 2015-12-14
Acq. date: 2025-11-13
Additional indexing
Creators (Authors)
- Di Chiara, Marianna
- Glaudemans, Bob
- Loffing-Cueni, Dominique
- Odermatt, Alex
- Al-Hasani, Hadi
- Devuyst, Olivier
- Faresse, Nourdine
- Loffing, Johannes
Journal/Series Title
Journal/Series Title
Journal/Series Title
Volume
Volume
Volume
309
Number
Number
Number
9
Page range/Item number
Page range/Item number
Page range/Item number
F779
Page end
Page end
Page end
F790
Item Type
Item Type
Item Type
Journal Article
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
English
Publication date
Publication date
Publication date
2015-11-01
Date available
Date available
Date available
2015-12-14
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1522-1466
Additional Information
Additional Information
Additional Information
All journals are free accessible after 12 months via HighWire Press
OA Status
OA Status
OA Status
Closed
Free Access at
Free Access at
Free Access at
DOI
Publisher DOI
Metrics
Views
184 since deposited on 2015-12-14
Acq. date: 2025-11-13
Closed
Loading...
No files available