Publication: A Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from Pseudomonas aeruginosa
Date
Date
Date
2018
Journal Article
Published version
Abstract
Abstract
Abstract
The outer membrane (OM) in Gram-negative bacteria is an asymmetric bilayer with mostly lipopolysaccharide (LPS) molecules in the outer leaflet. During OM biogenesis, new LPS molecules are transported from their site of assembly on the inner membrane to the OM by seven LPS transport proteins (LptA-G). The complex formed between the integral β-barrel OM protein LptD and the lipoprotein LptE is responsible for transporting LPS from the periplasmic side of the OM to its final location on the cell surface. Because of its essential function
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515 since deposited on 2018-04-26
Acq. date: 2025-11-13
Views
474 since deposited on 2018-04-26
Acq. date: 2025-11-13
Additional indexing
Creators (Authors)
- Andolina, Gloria
- Bencze, László-Csaba
- Zerbe, Katja
- Müller, Maik
- Steinmann, Jessica
- Kocherla, Harsha
- Mondal, Milon
- Sobek, Jens
- Moehle, Kerstin
- Malojčić, Goran
- Wollscheid, Bernd
- Robinson, John A
Volume
Volume
Volume
13
Number
Number
Number
3
Page range/Item number
Page range/Item number
Page range/Item number
666
Page end
Page end
Page end
675
Item Type
Item Type
Item Type
Journal Article
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
English
Publication date
Publication date
Publication date
2018-03-16
Date available
Date available
Date available
2018-04-26
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1554-8929
Additional Information
Additional Information
Additional Information
This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Chemical Biology, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see doi.org/10.1021/acschembio.7b00822.
OA Status
OA Status
OA Status
Green
Free Access at
Free Access at
Free Access at
DOI
Publisher DOI
Metrics
Downloads
515 since deposited on 2018-04-26
Acq. date: 2025-11-13
Views
474 since deposited on 2018-04-26
Acq. date: 2025-11-13
Green Open Access
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