Publication: FGF23 in Chronic Kidney Disease: Bridging the Heart and Anemia
FGF23 in Chronic Kidney Disease: Bridging the Heart and Anemia
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Figurek, A., Rroji, M., & Spasovski, G. (2023). FGF23 in Chronic Kidney Disease: Bridging the Heart and Anemia. Cells, 12, 609. https://doi.org/10.3390/cells12040609
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Abstract
Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone produced mainly in osteocytes. In chronic kidney disease (CKD) FGF23 levels increase due to higher production, but also as the result of impaired cleavage and reduced excretion from the body. FGF23 has a significant role in disturbed bone and mineral metabolism in CKD, which leads to a higher cardiovascular risk and mortality in these patients. Current research has emphasized the expression of FGF23 in cardiac myocytes, fibroblasts, and endothelial cells, and in addition to
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- Figurek, Andreja
- Rroji, Merita
- Spasovski, Goce
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Figurek, A., Rroji, M., & Spasovski, G. (2023). FGF23 in Chronic Kidney Disease: Bridging the Heart and Anemia. Cells, 12, 609. https://doi.org/10.3390/cells12040609
