Publication: ccz-1 mediates the digestion of apoptotic corpses in C. elegans
ccz-1 mediates the digestion of apoptotic corpses in C. elegans
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Nieto, C., Almendinger, J., Gysi, S., Gómez-Orte, E., Kaech, A., Hengartner, M. O., Schnabel, R., Moreno, S., & Cabello, J. (2010). ccz-1 mediates the digestion of apoptotic corpses in C. elegans. Journal of Cell Science, 123(12), 2001–2007. https://doi.org/10.1242/jcs.062331
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During development, the processes of cell division, differentiation and apoptosis must be precisely coordinated in order to maintain tissue homeostasis. The nematode C. elegans is a powerful model system in which to study cell death and its control. C. elegans apoptotic cells condense and form refractile corpses under differential interference contrast (DIC) microscopy. Activation of the GTPase CED-10 (Rac) in a neighbouring cell mediates the recognition and engulfment of the cell corpse. After inclusion of the engulfed corpse in a ph
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Nieto, C., Almendinger, J., Gysi, S., Gómez-Orte, E., Kaech, A., Hengartner, M. O., Schnabel, R., Moreno, S., & Cabello, J. (2010). ccz-1 mediates the digestion of apoptotic corpses in C. elegans. Journal of Cell Science, 123(12), 2001–2007. https://doi.org/10.1242/jcs.062331