Publication: A systematic meta-analysis of the association of Neuregulin 1 (NRG1), D-amino acid oxidase (DAO), and DAO activator (DAOA)/G72 polymorphisms with schizophrenia
A systematic meta-analysis of the association of Neuregulin 1 (NRG1), D-amino acid oxidase (DAO), and DAO activator (DAOA)/G72 polymorphisms with schizophrenia
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Jagannath, V., Gerstenberg, M., Correll, C. U., Walitza, S., & Grünblatt, E. (2018). A systematic meta-analysis of the association of Neuregulin 1 (NRG1), D-amino acid oxidase (DAO), and DAO activator (DAOA)/G72 polymorphisms with schizophrenia. Journal of Neural Transmission, 125(1), 89–102. https://doi.org/10.1007/s00702-017-1782-z
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The glutamate hypothesis of schizophrenia is related to the proposed dysregulation of D-amino acid oxidase (DAO), DAO activator (DAOA)/G72, and Neuregulin 1 (NRG1) genes. Genetic studies have shown significant associations between DAO, DAOA, NRG1 single-nucleotide polymorphisms (SNPs), and schizophrenia. The systematic literature search yielded 6, 5, and 18 new studies for DAO, DAOA, and NRG1 published after 2011 and not included in the previous SchizophreniaGene (SZGene) meta-analysis. We conducted meta-analyses of 20, 23, and 48 cas
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- Jagannath, Vinita
- Gerstenberg, Miriam
- Correll, Christoph U
- Grünblatt, Edna
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Jagannath, V., Gerstenberg, M., Correll, C. U., Walitza, S., & Grünblatt, E. (2018). A systematic meta-analysis of the association of Neuregulin 1 (NRG1), D-amino acid oxidase (DAO), and DAO activator (DAOA)/G72 polymorphisms with schizophrenia. Journal of Neural Transmission, 125(1), 89–102. https://doi.org/10.1007/s00702-017-1782-z
